Vitamin D insufficiency is associated with increased risk of developing long-term COVID-19

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People who are deficient in vitamin D after being hospitalized with COVID-19 may develop prolonged COVID-19 and experience negative cognitive effects, according to a new study. It is said to be expensive.Tatyana Maksimova/Getty Images
  • People who are deficient in vitamin D after being hospitalized with COVID-19 are more likely to develop long-lasting COVID-19 than those without vitamin D deficiency, a new study finds. revealed in a study.
  • This controlled study was designed to remove as many unknown variables as possible and produced what the authors consider to be robust findings.
  • The researchers assessed the participants’ vitamin D levels at discharge and again six months later, also testing them for long-term COVID-19 symptoms.
  • Symptoms associated with prolonged COVID-19 most likely to occur with vitamin D deficiency included negative cognitive effects.

About one in five adults in the U.S. who get COVID-19 will eventually develop a long-lasting COVID-19 infection, according to the U.S. Centers for Disease Control and Prevention (CDC).

However, a new study investigating the link between vitamin D deficiency and prolonged COVID-19 found that prolonged COVID-19 was associated with up to 50% of hospitalizations with COVID-19. 70% are affected.

Researchers looked at vitamin D levels in COVID-19 patients at admission and six months after discharge. They observed that people with long-term COVID-19 had lower vitamin D levels than those without.

Chief Researcher Dr. Andrea GiustinaProfessor of Endocrinology and Metabolism at the Vita Salute San Rafaele University in Milan, Italy. medical news today:

“Among the clinical areas of prolonged COVID-19, the more relevant effects of vitamin D insufficiency were found in the neurocognitive area.”

Research results have recently Journal of Clinical Endocrinology and Metabolism.

of World Health Organization (WHO) defines prolonged COVID-19 as the continuation or development of COVID-19-related symptoms within 3 months of acute SARS-CoV-2 infection. The symptoms can last for more than 2 months and have no other explanation.

of National Institute on Aging (NIH) It describes the following symptoms of long-term COVID-19:

  • tiredness or tiredness
  • have difficulty breathing or are short of breath
  • coughing
  • Experiencing joint pain and weakness
  • have hypertension
  • Notice changes in smell, taste, or both
  • confusion, forgetfulness, or fog in the head

For the study, the researchers recruited 50 people with a long-term diagnosis of COVID-19 and 50 who had no symptoms from an outpatient clinic associated with Milan’s San Raffaele Hospital. .

The two groups of individuals were matched one-to-one, taking into account severity of COVID-19 illness, age, gender, and pre-existing chronic disease.

Rigorously matching people with and without long-term COVID-19 was a means of avoiding possible influencing factors that could confound research results. It is difficult to explain the uncontrolled variables in vitamin D and long-term novel coronavirus studies.

At six months follow-up, the study authors found no observable differences between matched participants, other than vitamin D levels, suggesting that vitamin D deficiency causes long-lasting COVID-19 symptoms. suggested to be a factor.

The researchers also found that more severe vitamin D deficiency was most often associated with long-lasting neurocognitive symptoms synonymous with COVID-19.

Vitamin D clearly plays a role in maintaining bone health, explained Dr. Giustina. Among them, positive effects on the immune system are thought to play a role in this connection. ”

Ray Markssaid a lecturer in health behavior at Columbia University. MNT “It’s hard to refute,” he said, as other studies agree.

Dr. Marks noted that studies have shown that vitamin D impacts cognitive health, pain, obesity and bone health, all of which are linked to “long-term COVID-19 and multiple chronic diseases. parallel,” he said.

Similarly, low vitamin D levels in older people are a common finding, which can lead to other potentially long-lasting COVID-19 symptoms such as cognitive impairment, weakness and weakness, she added. rice field.

“The molecular mechanism of vitamin D alone suggests that vitamin D is a necessary cellular physiology and genetic mediator, and its deficiency has profound effects on the body. Thus, the results are as expected.” You can see it, but you have to think carefully about this.”

– Dr. Ray Marks

Dr. Marks also pointed out that other studies have shown that people with darker skin are more likely to have vitamin D deficiency.

for example, cooper lab reported that 76% of African Americans suffer from vitamin D deficiency. The melanin found in darker skin tones is believed to reduce the production of vitamin D.

Vitamin D is indirectly produced by sunlight. Ultraviolet B rays cause the skin to synthesize 7-dehydrocholesterol, a type of cholesterol, which the body uses to make vitamin D3 in the liver and then in the kidneys.

of National Institutes of Health (NIH) Most Americans have adequate levels of vitamin D in their blood, but one in four do not.

Dr. Marks cites air pollution as one of the wide-ranging factors that can contribute to low vitamin D levels.

The only way to know if you’re getting enough vitamin D is to have your doctor prescribe a vitamin D blood test.

The NIH recommends that adults between the ages of 19 and 70 take an average of 600 IU of vitamin D daily. Elderly he should take an average of 800 IU per day.

If blood test results show that you have vitamin D deficiency, your doctor will recommend a vitamin D supplement dosage that fits your needs.

When asked if vitamin D supplementation could help prevent long-term COVID-19 symptoms, Dr. Giustina said: “The Role of Vitamin D Supplementation in Preventing Long-Term COVID-19 Disease” [is] Not yet available. ”

Still, Dr. Giustina recommends post-hospital prophylaxis to check patients’ vitamin D levels and treat any deficiencies as needed.

“I am in favor of a safe daily level of vitamin D for everyone, both for prevention and recovery from multiple chronic health conditions, including obesity, an important analogue of COVID-19. said Dr. Marks.

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